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The Q0T065 knowlet was created by extracting all associated concepts from these representative publications:
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Knowlet for Q0T065
The Q0T065 Knowlet condenses the information pertaining to Q0T065 and shows only the connected concepts (direct connections shown in green, indirect connections shown in yellow).
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synonymsAndTranslations-
N-acetylneuraminate lyase
N-acetylneuraminate pyruvate-lyase
N-acetylneuraminic acid aldolase
Sialic acid lyase
Sialate lyase
Sialic acid aldolase
N-acetylneuraminate lyase (Shigella flexneri serotype 5b (strain 8401))
NANA_SHIF8
edit
- functional
-
gene product is element in pathway:
Amino-sugar metabolism; N-acetylneuraminic acid degradation; D-fructose 6-phosphate from N-acetylneuraminic acid: step 1/5.
has catalytic activity:
N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.
has function:
Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. (By similarity)
performs:
EC 4.1.3.3
gene product has molecular function:
N-acetylneuraminate lyase activity edit
- localization
-
has subcellular localization:
Cytoplasm. (By similarity)
occurs in:
Shigella flexneri serotype 5b (strain 8401) edit
- structural
-
component of:
Homotetramer. (By similarity)
gene product encoded by gene:
nanA (Shigella flexneri serotype 5b (strain 8401)) edit
- conceptual
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gene product plays role in biological process:
Carbohydrate Metabolism
similarity confers association with:
DHDPS family. NanA subfamily edit
- references
-
source:
Swiss-Prot edit
- classMembership
-
amino acid, peptide, or protein
N-acetylneuraminate lyase edit
